Новости

Прогресс в функциональном излечении от ВИЧ

Прогресс в функциональном излечении от ВИЧ

Управление по контролю качества пищевых продуктов и лекарственных препаратов США разрешило начать клинические испытания на человеке возможного способа функционального излечения от ВИЧ

По сообщению ресурса Medical Daily, Управление по контролю качества пищевых продуктов и лекарственных препаратов США (FDA) дало зеленый свет испытаниям на человеке генетической терапии против ВИЧ, которая может привести к функциональному излечению. Лечение представляет собой забор кроветворных стволовых клеток у ВИЧ-положительных участников исследования, у которых антиретровирусная (АРВ) терапия показала низкую эффективность. Далее исследователи на генетическом уровне «дадут инструкции» иммунным клеткам, чтобы сделать их устойчивыми к вирусу.

Для того, чтобы инфицировать иммунную клетку, ВИЧ необходимо сначала зацепиться за рецептор на поверхности этой клетки. ВИЧ в основном взаимодействует с рецептором CCR5. (Есть еще одни рецептор, CXCR4, который ВИЧ, как правило, начинает использовать на более поздних стадиях заболевания). Данная генная терапия должна привести к производству иммунных клеток, у которых отсутствует рецептор CCR5. Таким образом, будет предотвращена возможность первоначального контакта ВИЧ с клеткой. В идеале, эти иммунные клетки будут сохраняться вечно, сообщает aidsmeds.com.

В сентябре 2013 года были обнародованы многообещающие результаты, которые на второй стадии клинических испытаний показал схожий метод применения этого подхода к генной терапии. У одного из участников в течение долгого времени вирусная нагрузка оставалась неопределяемой, хотя он не принимал АРВ-терапию. Лечение также привело к долгосрочному увеличению у участников исследования количества клеток CD4 и соответствующему падению размера резервуара вируса.

Данное новое исследование является первой стадией клинических испытаний, то есть оно призвано лишь определить безопасность лечения. Чтобы новое лечение получило одобрение FDA, оно вначале должно пройти три стадии клинических испытаний, которые постепенно усложняются и увеличиваются в масштабе. Этот процесс может занять много лет.

Прогресс в функциональном излечении от ВИЧ

www.parniplus.com

Если вы нашли ошибку, пожалуйста, выделите фрагмент текста и нажмите Ctrl+Enter.

Не пропусти самые интересные статьи «Парни ПЛЮС» – подпишись на наши страницы в соцсетях!

Facebook | ВКонтакте | Telegram | Twitter | Помочь финансово
Яндекс.ДЗЕН | Youtube

Из этой же рубрики

172 Comments

  1. 1
  2. 2

    I am the business owner of JustCBD Store company (justcbdstore.com) and I’m presently planning to grow my wholesale side of business. I really hope that anybody at targetdomain is able to provide some guidance ! I thought that the most ideal way to accomplish this would be to talk to vape companies and cbd retailers. I was hoping if someone could suggest a trusted site where I can purchase Vape Shop Business Email Addresses I am presently checking out creativebeartech.com, theeliquidboutique.co.uk and wowitloveithaveit.com. Not exactly sure which one would be the very best selection and would appreciate any guidance on this. Or would it be much simpler for me to scrape my own leads? Ideas?

  3. 3
  4. 4
  5. 5

    You’re so interesting! I don’t suppose I have read through something like that before. So nice to discover another person with a few original thoughts on this issue. Really. many thanks for starting this up. This web site is one thing that is needed on the web, someone with a little originality!

  6. 6
  7. 7
  8. 8

    Having read this I believed it was really informative. I appreciate you taking the time and effort to put this informative article together. I once again find myself spending way too much time both reading and leaving comments. But so what, it was still worth it!

  9. 9
  10. 10
  11. 11

    An outstanding share! I have just forwarded this onto a coworker who had been conducting a little homework on this. And he in fact ordered me lunch due to the fact that I found it for him… lol. So let me reword this… Thanks for the meal! But yeah, thanks for spending some time to talk about this issue here on your website.

  12. 12
  13. 13
  14. 14

    When I originally left a comment I appear to have clicked on the -Notify me when new comments are added- checkbox and now each time a comment is added I get four emails with the same comment. Is there a way you can remove me from that service? Thanks!

  15. 15

    Hi, I do think this is a great web site. I stumbledupon it 😉 I will return once again since I bookmarked it. Money and freedom is the greatest way to change, may you be rich and continue to help others.

  16. 16

    A motivating discussion is definitely worth comment. I do believe that you need to write more about this issue, it may not be a taboo matter but typically folks don’t discuss such issues. To the next! Best wishes!

  17. 17
  18. 18
  19. 19
  20. 20
  21. 21

    Having read this I thought it was really informative. I appreciate you finding the time and energy to put this informative article together. I once again find myself personally spending a significant amount of time both reading and posting comments. But so what, it was still worth it!

  22. 22
  23. 23
  24. 24
  25. 25
  26. 26

    I simply want to say I am just beginner to blogging and site-building and absolutely enjoyed your blog site. Very likely I’m want to bookmark your site. You really have wonderful article content. Thank you for revealing your web site.

  27. 27
  28. 28
  29. 29
  30. 30
  31. 31
  32. 32
  33. 33
  34. 34

    I blog often and I really thank you for your content. This great article has truly peaked my interest. I’m going to book mark your website and keep checking for new information about once a week. I opted in for your Feed too.

  35. 35

    I would like to thank you for the efforts you have put in writing this site. I’m hoping to check out the same high-grade blog posts by you later on as well. In truth, your creative writing abilities has encouraged me to get my own website now 😉

  36. 36

    When I originally commented I appear to have clicked the -Notify me when new comments are added- checkbox and from now on every time a comment is added I receive four emails with the exact same comment. Perhaps there is an easy method you can remove me from that service? Cheers!

  37. 37

    Howdy! This article couldn’t be written any better! Going through this post reminds me of my previous roommate! He constantly kept preaching about this. I am going to send this information to him. Fairly certain he’ll have a good read. I appreciate you for sharing!

  38. 38

    Hello, i read your blog from time to time and i own a similar one and i was just curious if you get a lot of spam responses? If so how do you reduce it, any plugin or anything you can advise? I get so much lately it’s driving me insane so any help is very much appreciated.|

  39. 39
  40. 40

    May I just say what a comfort to find an individual who truly understands what they are talking about on the net. You actually realize how to bring a problem to light and make it important. More and more people should check this out and understand this side of the story. I was surprised that you aren’t more popular since you certainly have the gift.

  41. 41
  42. 42
  43. 43
  44. 44
  45. 45
  46. 46

    Hi there! This blog post could not be written any better! Looking through this post reminds me of my previous roommate! He continually kept preaching about this. I will send this information to him. Fairly certain he will have a great read. I appreciate you for sharing!

  47. 47
  48. 48
  49. 49

    I am really inspired together with your writing skills as neatly as with the structure in your blog. Is this a paid subject or did you modify it your self? Anyway stay up the excellent high quality writing, it is uncommon to peer a great weblog like this one these days.|

  50. 50
  51. 51

    Nice post. I learn something new and challenging on sites I stumbleupon on a daily basis. It’s always helpful to read articles from other authors and use something from their web sites.

  52. 52
  53. 53

    May I simply say what a relief to find a person that truly knows what they are discussing on the net. You certainly know how to bring a problem to light and make it important. More people really need to check this out and understand this side of the story. I can’t believe you are not more popular since you definitely have the gift.

  54. 54

    Hi there, just became aware of your blog through Google, and found that it is really informative. I am going to watch out for brussels. I’ll be grateful if you continue this in future. Lots of people will be benefited from your writing. Cheers!|

  55. 55
  56. 56
  57. 57
  58. 58

    I blog quite often and I seriously appreciate your content. This great article has really peaked my interest. I will take a note of your site and keep checking for new details about once a week. I subscribed to your RSS feed too.

  59. 59
  60. 60
  61. 61

    David-Home Northeast is your premier source for all of your Real Estate investing needs. We provide a variety of solutions for sellers looking to sell fast and investors looking to grow their real estate investment portfolios for better returns. At David-Home Northeast, we are dedicated to improving and redeveloping the areas that we operate in. We specialize in helping sellers of distressed properties (single and multi-family homes, commercial, retail, bank REOs, etc.) find buyers looking to invest. Let us put our network of cash home buyers and private money lenders to work for you so you can say «David» to that old unwanted property.

  62. 62
  63. 63
  64. 64
  65. 65
  66. 66
  67. 67
  68. 68
  69. 69
  70. 70
  71. 71

    Magnificent beat ! I wish to apprentice at the same time as you amend your website, how could i subscribe for a blog site? The account helped me a applicable deal. I had been tiny bit acquainted of this your broadcast offered bright clear idea

  72. 72
  73. 73
  74. 74
  75. 75

    I’m amazed, I must say. Rarely do I come across a blog that’s equally educative and engaging, and let me tell you, you’ve hit the nail on the head. The issue is something that too few folks are speaking intelligently about. Now i’m very happy that I found this during my search for something regarding this.

  76. 76
  77. 77

    Attractive part of content. I simply stumbled upon your weblog and in accession capital to assert that I get actually loved account your blog posts. Anyway I will be subscribing on your augment and even I fulfillment you access constantly quickly.

  78. 78
  79. 79
  80. 80
  81. 81
  82. 82

    A Psalm of David. The Lord is my shepherd; I shall not want. He makes me lie down in green pastures. He leads me beside still waters. He restores my soul. He leads me in paths of righteousness for his name’s sake. Even though I walk through the valley of the shadow of death, I will fear no evil, for you are with me; your rod and your staff, they comfort me. You prepare a table before me in the presence of my enemies; you anoint my head with oil; my cup overflows… Psalm 23:1−6 ESV

  83. 83
  84. 84
  85. 85

    Hiya, I’m really glad I’ve found this info. Today bloggers publish just about gossips and internet and this is really irritating. A good web site with exciting content, that’s what I need. Thanks for keeping this site, I will be visiting it. Do you do newsletters? Can not find it.

  86. 86
  87. 87
  88. 88
  89. 89
  90. 90
  91. 91

    Hi there just wanted to give you a quick heads up. The words in your article seem to be running off the screen in Chrome. I’m not sure if this is a formatting issue or something to do with web browser compatibility but I figured I’d post to let you know. The design look great though! Hope you get the issue solved soon. Kudos|

  92. 92
  93. 93
  94. 94
  95. 95
  96. 96
  97. 97
  98. 98
  99. 99
  100. 100

    I’ve been browsing online more than three hours lately, yet I never discovered any attention-grabbing article like yours. It’s pretty price sufficient for me. In my view, if all site owners and bloggers made just right content material as you probably did, the internet will be much more useful than ever before.|

  101. 101
  102. 102
  103. 103

    Good day! I could have sworn I’ve visited this site before but after looking at many of the posts I realized it’s new to me. Nonetheless, I’m definitely pleased I came across it and I’ll be book-marking it and checking back often!

  104. 104

    Hi there! I know this is kinda off topic nevertheless I’d figured I’d ask. Would you be interested in trading links or maybe guest authoring a blog article or vice-versa? My site covers a lot of the same subjects as yours and I feel we could greatly benefit from each other. If you might be interested feel free to send me an e-mail. I look forward to hearing from you! Wonderful blog by the way!

  105. 105
  106. 106
  107. 107

    Oh my goodness! an amazing article dude. Thanks However I’m experiencing issue with ur rss. Don’t know why Unable to subscribe to it. Is there anyone getting identical rss drawback? Anyone who knows kindly respond. Thnkx

  108. 108

    Pretty nice post. I just stumbled upon your weblog and wanted to say that I have really loved browsing your weblog posts. In any case I will be subscribing on your rss feed and I hope you write once more soon!

  109. 109

    I have been exploring for a little for any high quality articles or blog posts on this kind of area. Exploring in Yahoo I at last stumbled upon this web site. Reading this info So i am happy to convey that I’ve an incredibly good uncanny feeling I discovered exactly what I needed. I most certainly will make sure to do not forget this website and give it a look regularly.

  110. 110
  111. 111

    Hi there I am so excited I found your blog page, I really found you by mistake, while I was browsing on Aol for something else, Nonetheless I am here now and would just like to say thanks a lot for a tremendous post and a all round enjoyable blog (I also love the theme/design), I donĂ­t have time to look over it all at the minute but I have saved it and also added your RSS feeds, so when I have time I will be back to read much more, Please do keep up the fantastic job.

  112. 112
  113. 113
  114. 114
  115. 115
  116. 116
  117. 117

    I would like to thank you for the efforts you have put in writing this web site. I’m hoping the same high-grade site post from you in the upcoming also. Actually your creative writing skills has inspired me to get my own website now. Actually the blogging is spreading its wings fast. Your write up is a great example of it.

  118. 118
  119. 119

    Youre so amazing! I do not suppose Ive review anything like this before. So nice to locate someone with some initial thoughts on this subject. realy thanks for beginning this up. this web site is something that is needed on the internet, someone with a little originality. useful task for bringing something new to the net!

  120. 120

    I mastered more a new challenge on this fat reduction issue. 1 issue is that good nutrition is highly vital any time dieting. A huge reduction in bad foods, sugary food items, fried foods, sugary foods, red meat, and whitened flour products could possibly be necessary. Having wastes parasites, and wastes may prevent desired goals for losing belly fat. While specified drugs briefly solve the problem, the nasty side effects will not be worth it, and they also never offer more than a short lived solution. This is a known fact that 95 of dietary fads fail. Many thanks sharing your ideas on this blog.

  121. 121

    I’d like to thank you for the efforts you have put in writing this blog. I am hoping to check out the same high-grade blog posts by you in the future as well. In fact, your creative writing abilities has encouraged me to get my own, personal blog now 😉

  122. 122

    Can I simply just say what a comfort to uncover someone that genuinely knows what they’re talking about over the internet. You actually know how to bring an issue to light and make it important. More and more people have to look at this and understand this side of the story. I can’t believe you aren’t more popular given that you certainly possess the gift.

  123. 123

    I was pretty pleased to uncover this web site. I need to to thank you for your time for this fantastic read! I definitely really liked every little bit of it and i also have you bookmarked to see new stuff in your site.

  124. 124

    Hi there! I know this is somewhat off topic but I was wondering if you knew where I could locate a captcha plugin for my comment form? I’m using the same blog platform as yours and I’m having difficulty finding one? Thanks a lot!

  125. 125
  126. 126
  127. 127
  128. 128

    hey there and thank you for your info — I have definitely picked up anything new from right here. I did however expertise some technical issues using this site, since I experienced to reload the web site a lot of times previous to I could get it to load properly. I had been wondering if your web hosting is OK? Not that I am complaining, but slow loading instances times will sometimes affect your placement in google and can damage your quality score if advertising and marketing with Adwords. Anyway I’m adding this RSS to my email and can look out for much more of your respective exciting content. Ensure that you update this again very soon.

  129. 129

    Hey, I think your blog might be having browser compatibility issues. When I look at your blog site in Ie, it looks fine but when opening in Internet Explorer, it has some overlapping. I just wanted to give you a quick heads up! Other then that, great blog!

  130. 130
  131. 131
  132. 132

    Good web site! I really love how it is easy on my eyes and the data are well written. I’m wondering how I could be notified when a new post has been made. I have subscribed to your RSS which must do the trick! Have a great day!

  133. 133
  134. 134

    Good day! I could have sworn I’ve been to your blog before but after looking at a few of the articles I realized it’s new to me. Regardless, I’m certainly pleased I stumbled upon it and I’ll be book-marking it and checking back regularly!

  135. 135
  136. 136
  137. 137
  138. 138
  139. 139

    Woah! I’m really loving the template/theme of this blog. It’s simple, yet effective. A lot of times it’s tough to get that «perfect balance» between user friendliness and visual appeal. I must say that you’ve done a great job with this. In addition, the blog loads extremely quick for me on Internet explorer. Superb Blog!

  140. 140

    There are certainly a great deal of information like that to consider. That is a wonderful indicate raise. I use the ideas above as basic ideas but plainly there are questions like the one you raise where one of the most vital thing will be working in sincere good faith. I don? t understand if ideal practices have emerged around things like that, yet I am sure that your task is clearly identified as a level playing field. Both kids as well as women really feel the impact of simply a moment? s enjoyment, for the remainder of their lives.

  141. 141

    Hello would you mind sharing which blog platform you’re using? I’m planning to start my own blog in the near future but I’m having a hard time selecting between BlogEngine/Wordpress/B2evolution and Drupal. The reason I ask is because your design and style seems different then most blogs and I’m looking for something completely unique. P. S My apologies for being off-topic but I had to ask!

  142. 142
  143. 143

    Having read this I thought it was extremely enlightening. I appreciate you taking the time and energy to put this information together. I once again find myself personally spending way too much time both reading and leaving comments. But so what, it was still worthwhile!

  144. 144
  145. 145

    This is the best blog site for any person that intends to learn about this subject. You realize so much its practically hard to suggest with you (not that I really would want? HaHa). You absolutely placed a new spin on a topic thats been covered for many years. Wonderful things, just fantastic!

  146. 146

    Thank you a lot for giving everyone an extraordinarily breathtaking chance to discover important secrets from this site. It’s usually so amazing and also stuffed with fun for me personally and my office peers to visit the blog at the least 3 times per week to read the fresh things you have got. And lastly, we’re actually contented with your cool opinions served by you. Selected 2 tips on this page are definitely the most beneficial we have ever had.

  147. 147
  148. 148
  149. 149
  150. 150
  151. 151
  152. 152
  153. 153
  154. 154
  155. 155
  156. 156
  157. 157
  158. 158
  159. 159
  160. 160
  161. 161

    You’re so interesting! I don’t suppose I’ve truly read something like this before. So wonderful to find another person with a few unique thoughts on this issue. Really. thank you for starting this up. This website is one thing that is required on the internet, someone with some originality!

  162. 162
  163. 163
  164. 164
  165. 165

    I’d like to thank you for the efforts you’ve put in writing this site. I’m hoping to check out the same high-grade blog posts by you in the future as well. In fact, your creative writing abilities has encouraged me to get my very own site now 😉

  166. 166
  167. 167
  168. 168
  169. 169
  170. 170

    Oh my goodness! Incredible article dude! Many thanks, However I am having issues with your RSS. I don’t understand why I am unable to subscribe to it. Is there anybody else getting similar RSS problems? Anybody who knows the solution can you kindly respond? Thanks!

  171. 171
  172. 172

Добавить комментарий

Ваш адрес email не будет опубликован. Обязательные поля помечены *